Simultaneous solid–liquid separation and primary purification of clavulanic acid from fermentation broth of Streptomyces clavuligerus using salting‐out extraction system

Clavulanic acid (CA) is usually used together with other β‐lactam antibiotics as combination drugs to inhibit bacterial β‐lactamases, which is mainly produced from the fermentation of microorganism such as Streptomyces clavuligerus. Recently, it is still a challenge for downstream processing of low...

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Detalles Bibliográficos
Autores principales: Wang, Xu‐Dong, Hu, Chun‐Yan, Qin, Chao, Dong, Yue‐Sheng, Ying, Guo‐Qing, Xiu, Zhi‐Long, Su, Zhi‐Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518655/
https://www.ncbi.nlm.nih.gov/pubmed/34690635
http://dx.doi.org/10.1002/elsc.202000091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518655/
https://www.ncbi.nlm.nih.gov/pubmed/34690635
http://dx.doi.org/10.1002/elsc.202000091

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