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Evaluation of Pharmacokinetics, Safety, and Drug‐Drug Interactions of an Oral Suspension of Edaravone in Healthy Adults

Intravenous (IV) edaravone is approved as an amyotrophic lateral sclerosis (ALS) treatment. Because IV administration places a burden on patients, development of orally administered ALS treatments is needed. Therefore, 2 phase 1 studies of oral formulations of edaravone in healthy subjects examined...

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Detalles Bibliográficos
Autores principales: Shimizu, Hidetoshi, Nishimura, Yukiko, Shiide, Yoichi, Matsuda, Hideaki, Akimoto, Makoto, Matsuda, Munetomo, Nakamaru, Yoshinobu, Kato, Yuichiro, Kondo, Kazuoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518673/
https://www.ncbi.nlm.nih.gov/pubmed/33704925
http://dx.doi.org/10.1002/cpdd.925