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The human WNT5A isoforms display similar patterns of expression but distinct and overlapping activities in normal human osteoblasts

WNT5A activates noncanonical Wnt signaling pathways and has critical functions in early development, differentiation, and tissue homeostasis. Two major WNT5A protein isoforms, which in this study we term WNT5A‐L(A) and WNT5A‐S(B), have been identified that differ by 18 AA at their amino terminus. Fu...

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Detalles Bibliográficos
Autores principales: Bhandari, Dristi, Elshaarrawi, Ahmed, Katula, Karen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518764/
https://www.ncbi.nlm.nih.gov/pubmed/33982816
http://dx.doi.org/10.1002/jcb.29950