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Screening for New Inhibitors of Glycine Transporter 1 and 2 by Means of MS Binding Assays

A straightforward screening of a compound library comprising 2439 substances for the identification of new inhibitors for the neurotransmitter transporters GlyT1 and GlyT2 is described. Screening and full‐scale competition experiments were performed using recently developed GlyT1 and GlyT2 MS Bindin...

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Detalles Bibliográficos
Autores principales: Ackermann, Thomas M., Höfner, Georg, Wanner, Klaus T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518836/
https://www.ncbi.nlm.nih.gov/pubmed/34174033
http://dx.doi.org/10.1002/cmdc.202100408