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Screening for New Inhibitors of Glycine Transporter 1 and 2 by Means of MS Binding Assays
A straightforward screening of a compound library comprising 2439 substances for the identification of new inhibitors for the neurotransmitter transporters GlyT1 and GlyT2 is described. Screening and full‐scale competition experiments were performed using recently developed GlyT1 and GlyT2 MS Bindin...
Autores principales: | Ackermann, Thomas M., Höfner, Georg, Wanner, Klaus T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518836/ https://www.ncbi.nlm.nih.gov/pubmed/34174033 http://dx.doi.org/10.1002/cmdc.202100408 |
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