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Evaluation of 4‐(4‐Fluorobenzyl)piperazin‐1‐yl]‐Based Compounds as Competitive Tyrosinase Inhibitors Endowed with Antimelanogenic Effects

There is a considerable attention for the development of inhibitors of tyrosinase (TYR) as therapeutic strategy for the treatment of hyperpigmentation disorders in humans. Continuing in our efforts to identify TYR inhibitors, we describe the design, synthesis and pharmacophore exploration of new sma...

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Detalles Bibliográficos
Autores principales: Mirabile, Salvatore, Vittorio, Serena, Paola Germanò, Maria, Adornato, Ilenia, Ielo, Laura, Rapisarda, Antonio, Gitto, Rosaria, Pintus, Francesca, Fais, Antonella, De Luca, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518915/
https://www.ncbi.nlm.nih.gov/pubmed/34223697
http://dx.doi.org/10.1002/cmdc.202100396