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Evaluation of 4‐(4‐Fluorobenzyl)piperazin‐1‐yl]‐Based Compounds as Competitive Tyrosinase Inhibitors Endowed with Antimelanogenic Effects
There is a considerable attention for the development of inhibitors of tyrosinase (TYR) as therapeutic strategy for the treatment of hyperpigmentation disorders in humans. Continuing in our efforts to identify TYR inhibitors, we describe the design, synthesis and pharmacophore exploration of new sma...
Autores principales: | Mirabile, Salvatore, Vittorio, Serena, Paola Germanò, Maria, Adornato, Ilenia, Ielo, Laura, Rapisarda, Antonio, Gitto, Rosaria, Pintus, Francesca, Fais, Antonella, De Luca, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518915/ https://www.ncbi.nlm.nih.gov/pubmed/34223697 http://dx.doi.org/10.1002/cmdc.202100396 |
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