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Oxidized low‐density lipoprotein activates extracellular signal‐regulated kinase signaling to downregulate sortilin expression in liver sinusoidal endothelial cells
BACKGROUND AND AIM: Both type 2 diabetes mellitus and non‐alcoholic fatty liver disease are closely associated with elevated levels of low‐density lipoprotein cholesterol and its oxidized form (ox‐LDL). This study aimed to investigate the regulation of sortilin in liver tissue and its potential impl...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518938/ https://www.ncbi.nlm.nih.gov/pubmed/33694195 http://dx.doi.org/10.1111/jgh.15486 |