Oxidized low‐density lipoprotein activates extracellular signal‐regulated kinase signaling to downregulate sortilin expression in liver sinusoidal endothelial cells

BACKGROUND AND AIM: Both type 2 diabetes mellitus and non‐alcoholic fatty liver disease are closely associated with elevated levels of low‐density lipoprotein cholesterol and its oxidized form (ox‐LDL). This study aimed to investigate the regulation of sortilin in liver tissue and its potential impl...

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Detalles Bibliográficos
Autores principales: Zhang, Qi, Lin, Wenyan, Tian, Limin, Di, Baoshan, Yu, Jing, Niu, Xiang'e, Liu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Experimental Hepatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518938/
https://www.ncbi.nlm.nih.gov/pubmed/33694195
http://dx.doi.org/10.1111/jgh.15486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518938/
https://www.ncbi.nlm.nih.gov/pubmed/33694195
http://dx.doi.org/10.1111/jgh.15486

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