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A Chiral Lanthanide Tag for Stable and Rigid Attachment to Single Cysteine Residues in Proteins for NMR, EPR and Time‐Resolved Luminescence Studies

A lanthanide‐binding tag site‐specifically attached to a protein presents a tool to probe the protein by multiple spectroscopic techniques, including nuclear magnetic resonance, electron paramagnetic resonance and time‐resolved luminescence spectroscopy. Here a new stable chiral Ln(III) tag, referre...

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Detalles Bibliográficos
Autores principales: Herath, Iresha D., Breen, Colum, Hewitt, Sarah H., Berki, Thomas R., Kassir, Ahmad F., Dodson, Charlotte, Judd, Martyna, Jabar, Shereen, Cox, Nicholas, Otting, Gottfried, Butler, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518945/
https://www.ncbi.nlm.nih.gov/pubmed/34152643
http://dx.doi.org/10.1002/chem.202101143