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Multiple Occurrences of a 168-Nucleotide Deletion in SARS-CoV-2 ORF8, Unnoticed by Standard Amplicon Sequencing and Variant Calling Pipelines

Genomic surveillance of the SARS-CoV-2 pandemic is crucial and mainly achieved by amplicon sequencing protocols. Overlapping tiled-amplicons are generated to establish contiguous SARS-CoV-2 genome sequences, which enable the precise resolution of infection chains and outbreaks. We investigated a SAR...

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Detalles Bibliográficos
Autores principales: Brandt, David, Simunovic, Marina, Busche, Tobias, Haak, Markus, Belmann, Peter, Jünemann, Sebastian, Schulz, Tizian, Klages, Levin Joe, Vinke, Svenja, Beckstette, Michael, Pohl, Ehmke, Scherer, Christiane, Sczyrba, Alexander, Kalinowski, Jörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518987/
https://www.ncbi.nlm.nih.gov/pubmed/34578452
http://dx.doi.org/10.3390/v13091870