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Vorinostat ameliorates IL‐1α‐induced reduction of type II collagen by inhibiting the expression of ELF3 in chondrocytes

Osteoarthritis (OA) is a common joint disease that ultimately causes physical disability and imposes an economic burden on society. Cartilage destruction plays a key role in the development of OA. Vorinostat is an oral histone deacetylase (HDAC) inhibitor and has been used for the treatment of T‐cel...

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Detalles Bibliográficos
Autores principales: Miao, Xudong, Wu, Yongping, Wang, Ping, Zhang, Qiang, Zhou, Chenhe, Yu, Xinning, Cao, Le
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519056/
https://www.ncbi.nlm.nih.gov/pubmed/34250664
http://dx.doi.org/10.1002/jbt.22844