A Functional Variant on 9p21.3 Related to Glioma Risk Affects Enhancer Activity and Modulates Expression of CDKN2B‐AS1

Genome‐wide association studies have identified SNPs associated with glioma risk on 9p21.3, but biological mechanisms underlying this association are unknown. We tested the hypothesis that a functional SNP on 9p21.3 affects activity of an enhancer, causing altered expression of nearby genes. We cons...

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Detalles Bibliográficos
Autores principales: Ali, Mourad Wagdy, Patro, C. Pawan K., Devall, Matthew, Dampier, Christopher H., Plummer, Sarah J., Kuscu, Cem, Adli, Mazhar, Lai, Rose K., Casey, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519084/
https://www.ncbi.nlm.nih.gov/pubmed/34153138
http://dx.doi.org/10.1002/humu.24244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519084/
https://www.ncbi.nlm.nih.gov/pubmed/34153138
http://dx.doi.org/10.1002/humu.24244

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