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Attenuation of Doxorubicin‐Induced Small Intestinal Mucositis by Pectins is Dependent on Pectin's Methyl‐Ester Number and Distribution

SCOPE: Intestinal mucositis is a common side effect of the chemotherapeutic agent doxorubicin, which is characterized by severe Toll‐like receptor (TLR) 2‐mediated inflammation. The dietary fiber pectin is shown to prevent this intestinal inflammation through direct inhibition of TLR2 in a microbiot...

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Detalles Bibliográficos
Autores principales: Beukema, Martin, Jermendi, Éva, Koster, Taco, Kitaguchi, Kohji, de Haan, Bart J., van den Berg, Marco Alexander, Faas, Marijke M., Schols, Henk A., de Vos, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519125/
https://www.ncbi.nlm.nih.gov/pubmed/34268870
http://dx.doi.org/10.1002/mnfr.202100222