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Attenuation of Doxorubicin‐Induced Small Intestinal Mucositis by Pectins is Dependent on Pectin's Methyl‐Ester Number and Distribution
SCOPE: Intestinal mucositis is a common side effect of the chemotherapeutic agent doxorubicin, which is characterized by severe Toll‐like receptor (TLR) 2‐mediated inflammation. The dietary fiber pectin is shown to prevent this intestinal inflammation through direct inhibition of TLR2 in a microbiot...
Autores principales: | Beukema, Martin, Jermendi, Éva, Koster, Taco, Kitaguchi, Kohji, de Haan, Bart J., van den Berg, Marco Alexander, Faas, Marijke M., Schols, Henk A., de Vos, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519125/ https://www.ncbi.nlm.nih.gov/pubmed/34268870 http://dx.doi.org/10.1002/mnfr.202100222 |
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