Continuous Flow Acylation of (Hetero)aryllithiums with Polyfunctional N,N‐Dimethylamides and Tetramethylurea in Toluene

The continuous flow reaction of various aryl or heteroaryl bromides in toluene in the presence of THF (1.0 equiv) with sec‐BuLi (1.1 equiv) provided at 25 °C within 40 sec the corresponding aryllithiums which were acylated with various functionalized N,N‐dimethylamides including easily enolizable am...

Descripción completa

Detalles Bibliográficos
Autores principales: Djukanovic, Dimitrije, Heinz, Benjamin, Mandrelli, Francesca, Mostarda, Serena, Filipponi, Paolo, Martin, Benjamin, Knochel, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519161/
https://www.ncbi.nlm.nih.gov/pubmed/34387898
http://dx.doi.org/10.1002/chem.202102805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519161/
https://www.ncbi.nlm.nih.gov/pubmed/34387898
http://dx.doi.org/10.1002/chem.202102805

Ejemplares similares