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Lymphocyte-depleted classic Hodgkin lymphoma with primary extranodal disease: Two cases that highlight the combination of immunodeficiency and immune escape in the pathogenesis

Neoplastic programmed cell death ligand 1 (PD-L1) expression, activated by PD-L1 gene alterations, is strongly associated with classic Hodgkin lymphoma (CHL). This association enabled a diagnostic consensus for lymphocyte-depleted CHL (LD-CHL), a previously enigmatic disease. We describe two patient...

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Detalles Bibliográficos
Autores principales: Tsuyuki, Yuta, Kohno, Kei, Inagaki, Yuichiro, Sakai, Yu, Kosugi, Hiroshi, Takahashi, Emiko, Suzuki, Yuka, Shimada, Satoko, Kato, Seiichi, Takahara, Taishi, Satou, Akira, Shimoyama, Yoshie, Nakamura, Shigeo, Asano, Naoko, Sakakibara, Ayako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JSLRT 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519246/
https://www.ncbi.nlm.nih.gov/pubmed/34511545
http://dx.doi.org/10.3960/jslrt.21008