Isoform-Specific Reduction of the Basic Helix-Loop-Helix Transcription Factor TCF4 Levels in Huntington’s Disease

Huntington’s disease (HD) is an inherited neurodegenerative disorder with onset of characteristic motor symptoms at midlife, preceded by subtle cognitive and behavioral disturbances. Transcriptional dysregulation emerges early in the disease course and is considered central to HD pathogenesis. Using...

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Detalles Bibliográficos
Autores principales: Nurm, Kaja, Sepp, Mari, Castany-Pladevall, Carla, Creus-Muncunill, Jordi, Tuvikene, Jürgen, Sirp, Alex, Vihma, Hanna, Blake, Derek J., Perez-Navarro, Esther, Timmusk, Tõnis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Research Article: New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519306/
https://www.ncbi.nlm.nih.gov/pubmed/34518368
http://dx.doi.org/10.1523/ENEURO.0197-21.2021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519306/
https://www.ncbi.nlm.nih.gov/pubmed/34518368
http://dx.doi.org/10.1523/ENEURO.0197-21.2021

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