Structural analysis of the boronic acid β-lactamase inhibitor vaborbactam binding to Pseudomonas aeruginosa penicillin-binding protein 3

Antimicrobial resistance (AMR) mediated by β-lactamases is the major and leading cause of resistance to penicillins and cephalosporins among Gram-negative bacteria. β-Lactamases, periplasmic enzymes that are widely distributed in the bacterial world, protect penicillin-binding proteins (PBPs), the m...

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Detalles Bibliográficos
Autores principales: Kumar, Vijay, Viviani, Samantha L., Ismail, Jeeda, Agarwal, Shreya, Bonomo, Robert A., van den Akker, Focco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519428/
https://www.ncbi.nlm.nih.gov/pubmed/34653211
http://dx.doi.org/10.1371/journal.pone.0258359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519428/
https://www.ncbi.nlm.nih.gov/pubmed/34653211
http://dx.doi.org/10.1371/journal.pone.0258359

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