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Structural analysis of the boronic acid β-lactamase inhibitor vaborbactam binding to Pseudomonas aeruginosa penicillin-binding protein 3

Antimicrobial resistance (AMR) mediated by β-lactamases is the major and leading cause of resistance to penicillins and cephalosporins among Gram-negative bacteria. β-Lactamases, periplasmic enzymes that are widely distributed in the bacterial world, protect penicillin-binding proteins (PBPs), the m...

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Detalles Bibliográficos
Autores principales:	Kumar, Vijay, Viviani, Samantha L., Ismail, Jeeda, Agarwal, Shreya, Bonomo, Robert A., van den Akker, Focco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519428/ https://www.ncbi.nlm.nih.gov/pubmed/34653211 http://dx.doi.org/10.1371/journal.pone.0258359

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