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Unusual features and localization of the membrane kinome of Trypanosoma brucei

In many eukaryotes, multiple protein kinases are situated in the plasma membrane where they respond to extracellular ligands. Ligand binding elicits a signal that is transmitted across the membrane, leading to activation of the cytosolic kinase domain. Humans have over 100 receptor protein kinases....

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Detalles Bibliográficos
Autores principales: Jensen, Bryan C., Vaney, Pashmi, Flaspohler, John, Coppens, Isabelle, Parsons, Marilyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519429/
https://www.ncbi.nlm.nih.gov/pubmed/34653230
http://dx.doi.org/10.1371/journal.pone.0258814