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Loss of prion protein control of glucose metabolism promotes neurodegeneration in model of prion diseases
Corruption of cellular prion protein (PrP(C)) function(s) at the plasma membrane of neurons is at the root of prion diseases, such as Creutzfeldt-Jakob disease and its variant in humans, and Bovine Spongiform Encephalopathies, better known as mad cow disease, in cattle. The roles exerted by PrP(C),...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519435/ https://www.ncbi.nlm.nih.gov/pubmed/34610054 http://dx.doi.org/10.1371/journal.ppat.1009991 |