Loss of prion protein control of glucose metabolism promotes neurodegeneration in model of prion diseases

Corruption of cellular prion protein (PrP(C)) function(s) at the plasma membrane of neurons is at the root of prion diseases, such as Creutzfeldt-Jakob disease and its variant in humans, and Bovine Spongiform Encephalopathies, better known as mad cow disease, in cattle. The roles exerted by PrP(C),...

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Detalles Bibliográficos
Autores principales: Arnould, Hélène, Baudouin, Vincent, Baudry, Anne, Ribeiro, Luiz W., Ardila-Osorio, Hector, Pietri, Mathéa, Caradeuc, Cédric, Soultawi, Cynthia, Williams, Declan, Alvarez, Marjorie, Crozet, Carole, Djouadi, Fatima, Laforge, Mireille, Bertho, Gildas, Kellermann, Odile, Launay, Jean-Marie, Schmitt-Ulms, Gerold, Schneider, Benoit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519435/
https://www.ncbi.nlm.nih.gov/pubmed/34610054
http://dx.doi.org/10.1371/journal.ppat.1009991

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