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GRAFIMO: Variant and haplotype aware motif scanning on pangenome graphs

Transcription factors (TFs) are proteins that promote or reduce the expression of genes by binding short genomic DNA sequences known as transcription factor binding sites (TFBS). While several tools have been developed to scan for potential occurrences of TFBS in linear DNA sequences or reference ge...

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Detalles Bibliográficos
Autores principales: Tognon, Manuel, Bonnici, Vincenzo, Garrison, Erik, Giugno, Rosalba, Pinello, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519448/
https://www.ncbi.nlm.nih.gov/pubmed/34570769
http://dx.doi.org/10.1371/journal.pcbi.1009444