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Tau fibril with membrane lipids: Insight from computational modeling and simulations
The microtubule-binding protein tau has been the center of researches concerning Alzheimer’s disease (AD) due to several clinical trials of β-amyloid therapies failing recently. The availability of the tau fibril structure from AD brain enables computational modeling studies to calculate binding aff...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519458/ https://www.ncbi.nlm.nih.gov/pubmed/34653235 http://dx.doi.org/10.1371/journal.pone.0258692 |