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Molecular Insight into the Effect of a Single-Nucleotide Polymorphic Variation on the Structure and Dynamics of Methionine Synthase Reductase and Its Association with Neural Tube Defects

[Image: see text] Neural tube defects (NTDs) are among the common and severe congenital malformations in neonates. According to a WHO report, nearly three lakh babies are affected per year worldwide by NTDs. Most studies revealed that folate deficiency is the key element to promote NTD with other ol...

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Detalles Bibliográficos
Autores principales: Sadhukhan, Susanta, Maity, Subhajit, Chakraborty, Sandipan, Paul, Silpita, Munian, Dinesh, Pattanayak, Arup Kumar, Jana, Biman, Das, Madhusudan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519501/
https://www.ncbi.nlm.nih.gov/pubmed/34667917
http://dx.doi.org/10.1021/acsomega.1c03563