Block catiomer with flexible cationic segment enhances complexation with siRNA and the delivery performance in vitro

RNA interference (RNAi) by small interfering RNAs (siRNAs) is a promising therapeutic approach. Because siRNA has limited intracellular access and is rapidly cleared in vivo, the success of RNAi depends on efficient delivery technologies. Particularly, polyion complexation between block catiomers an...

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Detalles Bibliográficos
Autores principales: Yang, Wenqian, Miyazaki, Takuya, Chen, Pengwen, Hong, Taehun, Naito, Mitsuru, Miyahara, Yuji, Matsumoto, Akira, Kataoka, Kazunori, Miyata, Kanjiro, Cabral, Horacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Bio-Inspired and Biomedical Materials
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519541/
https://www.ncbi.nlm.nih.gov/pubmed/34658669
http://dx.doi.org/10.1080/14686996.2021.1976055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519541/
https://www.ncbi.nlm.nih.gov/pubmed/34658669
http://dx.doi.org/10.1080/14686996.2021.1976055

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