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Complete three-dimensional structures of the Lon protease translocating a protein substrate

Lon is an evolutionarily conserved proteolytic machine carrying out a wide spectrum of biological activities by degrading misfolded damaged proteins and specific cellular substrates. Lon contains a large N-terminal domain and forms a hexameric core of fused adenosine triphosphatase and protease doma...

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Detalles Bibliográficos
Autores principales: Li, Shanshan, Hsieh, Kan-Yen, Kuo, Chiao-I, Lee, Szu-Hui, Pintilie, Grigore D., Zhang, Kaiming, Chang, Chung-I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519571/
https://www.ncbi.nlm.nih.gov/pubmed/34652947
http://dx.doi.org/10.1126/sciadv.abj7835