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Progressive alterations in amino acid and lipid metabolism correlate with peripheral neuropathy in Polg(D257A) mice
Mitochondria are central to metabolic homeostasis, and progressive mitochondrial defects have diverse metabolic consequences that could drive distinct pathophysiological states. Here, we comprehensively characterized metabolic alterations in Polg(D257A) mice. Plasma alanine increased markedly with t...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519573/ https://www.ncbi.nlm.nih.gov/pubmed/34652935 http://dx.doi.org/10.1126/sciadv.abj4077 |