Canonical DNA non-homologous end-joining; capacity versus fidelity

The significance of canonical DNA non-homologous end-joining (c-NHEJ) for DNA double strand break (DSB) repair has increased from lower organisms to higher eukaryotes, and plays the predominant role in human cells. Ku, the c-NHEJ end-binding component, binds DSBs with high efficiency enabling c-NHEJ...

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Detalles Bibliográficos
Autores principales: Shibata, Atsushi, Jeggo, Penny A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Institute of Radiology. 2020
Materias:
Advances in radiation biology – Highlights from 16th ICRR special feature: Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519634/
https://www.ncbi.nlm.nih.gov/pubmed/31944860
http://dx.doi.org/10.1259/bjr.20190966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519634/
https://www.ncbi.nlm.nih.gov/pubmed/31944860
http://dx.doi.org/10.1259/bjr.20190966

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