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One end to rule them all: Non-homologous end-joining and homologous recombination at DNA double-strand breaks
Double-strand breaks (DSBs) represent the most severe type of DNA damage since they can lead to genomic rearrangements, events that can initiate and promote tumorigenic processes. DSBs arise from various exogenous agents that induce two single-strand breaks at opposite locations in the DNA double he...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The British Institute of Radiology.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519636/ https://www.ncbi.nlm.nih.gov/pubmed/32105514 http://dx.doi.org/10.1259/bjr.20191054 |