Cargando…

One end to rule them all: Non-homologous end-joining and homologous recombination at DNA double-strand breaks

Double-strand breaks (DSBs) represent the most severe type of DNA damage since they can lead to genomic rearrangements, events that can initiate and promote tumorigenic processes. DSBs arise from various exogenous agents that induce two single-strand breaks at opposite locations in the DNA double he...

Descripción completa

Detalles Bibliográficos
Autores principales: Ensminger, Michael, Löbrich, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Institute of Radiology. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519636/
https://www.ncbi.nlm.nih.gov/pubmed/32105514
http://dx.doi.org/10.1259/bjr.20191054