Canine DVL2 variant contributes to brachycephalic phenotype and caudal vertebral anomalies

A frameshift deletion variant in the Wnt pathway gene dishevelled 2 (DVL2) is associated with a truncated, kinked tail (“screw tail”) in English Bulldogs, French Bulldogs and Boston Terriers. These breeds are also characterized by distinctive morphological traits, including a wide head, flat face an...

Descripción completa

Detalles Bibliográficos
Autores principales: Niskanen, Julia E., Reunanen, Vilma, Salonen, Milla, Bannasch, Danika, Lappalainen, Anu K., Lohi, Hannes, Hytönen, Marjo K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519842/
https://www.ncbi.nlm.nih.gov/pubmed/33599851
http://dx.doi.org/10.1007/s00439-021-02261-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519842/
https://www.ncbi.nlm.nih.gov/pubmed/33599851
http://dx.doi.org/10.1007/s00439-021-02261-8

Ejemplares similares