Ketamine increases activity of a fronto-striatal projection that regulates compulsive behavior in SAPAP3 knockout mice

Obsessive-Compulsive Disorder (OCD), characterized by intrusive thoughts (obsessions) and repetitive behaviors (compulsions), is associated with dysfunction in fronto-striatal circuits. There are currently no fast-acting pharmacological treatments for OCD. However, recent clinical studies demonstrat...

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Detalles Bibliográficos
Autores principales: Davis, Gwynne L., Minerva, Adelaide R., Lario, Argentina, Simmler, Linda D., Rodriguez, Carolyn I., Gunaydin, Lisa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519915/
https://www.ncbi.nlm.nih.gov/pubmed/34654803
http://dx.doi.org/10.1038/s41467-021-26247-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519915/
https://www.ncbi.nlm.nih.gov/pubmed/34654803
http://dx.doi.org/10.1038/s41467-021-26247-2

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