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Photoactivatable ribonucleosides mark base-specific RNA-binding sites

RNA-protein interaction can be captured by crosslinking and enrichment followed by tandem mass spectrometry, but it remains challenging to pinpoint RNA-binding sites (RBSs) or provide direct evidence for RNA-binding. To overcome these limitations, we here developed pRBS-ID, by incorporating the bene...

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Detalles Bibliográficos
Autores principales: Bae, Jong Woo, Kim, Sangtae, Kim, V. Narry, Kim, Jong-Seo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519950/
https://www.ncbi.nlm.nih.gov/pubmed/34654832
http://dx.doi.org/10.1038/s41467-021-26317-5