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Elevated serum levels of methylglyoxal are associated with impaired liver function in patients with liver cirrhosis

Methylglyoxal (MGO) is a highly reactive dicarbonyl species that forms advanced glycation end products (AGEs). The binding of these AGEs to their receptor (RAGE) causes and sustains severe inflammation. Systemic inflammation is postulated to be a major driver in the progression of liver cirrhosis. H...

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Detalles Bibliográficos
Autores principales: Michel, Maurice, Hess, Cornelius, Kaps, Leonard, Kremer, Wolfgang M., Hilscher, Max, Galle, Peter R., Moehler, Markus, Schattenberg, Jörn M., Wörns, Marcus-Alexander, Labenz, Christian, Nagel, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519993/
https://www.ncbi.nlm.nih.gov/pubmed/34654829
http://dx.doi.org/10.1038/s41598-021-00119-7