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Elevated serum levels of methylglyoxal are associated with impaired liver function in patients with liver cirrhosis
Methylglyoxal (MGO) is a highly reactive dicarbonyl species that forms advanced glycation end products (AGEs). The binding of these AGEs to their receptor (RAGE) causes and sustains severe inflammation. Systemic inflammation is postulated to be a major driver in the progression of liver cirrhosis. H...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519993/ https://www.ncbi.nlm.nih.gov/pubmed/34654829 http://dx.doi.org/10.1038/s41598-021-00119-7 |