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From the niche to malignant hematopoiesis and back: reciprocal interactions between leukemia and the bone marrow microenvironment

The bone marrow microenvironment (BMME) regulates hematopoiesis through a complex network of cellular and molecular components. Hematologic malignancies reside within, and extensively interact with, the same BMME. These interactions consequently alter both malignant and benign hematopoiesis in multi...

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Detalles Bibliográficos
Autores principales: Soto, Celia A., Lo Celso, Cristina, Purton, Louise E., Frisch, Benjamin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520063/
https://www.ncbi.nlm.nih.gov/pubmed/34693187
http://dx.doi.org/10.1002/jbm4.10516