Effect of the spatial–temporal specific theca cell Cyp17 overexpression on the reproductive phenotype of the novel TC17 mouse

BACKGROUND: In the ovarian follicle, the Theca Cells (TCs) have two main functions: preserving morphological integrity and, importantly, secreting steroid androgen hormones. TCs express the essential enzyme 17α-hydroxylase/17,20-desmolase (CYP17), which permits the conversion of pregnenolone and pro...

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Detalles Bibliográficos
Autores principales: Secchi, Christian, Belli, Martina, Harrison, Tracy N. H., Swift, Joseph, Ko, CheMyong, Duleba, Antoni J., Stupack, Dwayne, Chang, R. Jeffrey, Shimasaki, Shunichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520195/
https://www.ncbi.nlm.nih.gov/pubmed/34654452
http://dx.doi.org/10.1186/s12967-021-03103-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520195/
https://www.ncbi.nlm.nih.gov/pubmed/34654452
http://dx.doi.org/10.1186/s12967-021-03103-x

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