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Effect of the spatial–temporal specific theca cell Cyp17 overexpression on the reproductive phenotype of the novel TC17 mouse

BACKGROUND: In the ovarian follicle, the Theca Cells (TCs) have two main functions: preserving morphological integrity and, importantly, secreting steroid androgen hormones. TCs express the essential enzyme 17α-hydroxylase/17,20-desmolase (CYP17), which permits the conversion of pregnenolone and pro...

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Detalles Bibliográficos
Autores principales:	Secchi, Christian, Belli, Martina, Harrison, Tracy N. H., Swift, Joseph, Ko, CheMyong, Duleba, Antoni J., Stupack, Dwayne, Chang, R. Jeffrey, Shimasaki, Shunichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520195/ https://www.ncbi.nlm.nih.gov/pubmed/34654452 http://dx.doi.org/10.1186/s12967-021-03103-x

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