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Age, vascular disease, and Alzheimer’s disease pathologies in amyloid negative elderly adults

BACKGROUND: We recently reported that CSF phosphorylated tau (p-Tau(181)) relative to Aβ(40) (CSF p-Tau/Aβ(40) ratio) was less noisy and increased associations with Alzheimer’s disease (AD) biomarkers compared to CSF p-Tau(181) alone. While elevations of CSF p-Tau/Aβ(40) can occur in amyloid-β (Aβ)...

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Detalles Bibliográficos
Autores principales: Guo, Tengfei, Landau, Susan M., Jagust, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520216/
https://www.ncbi.nlm.nih.gov/pubmed/34654465
http://dx.doi.org/10.1186/s13195-021-00913-5