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Functional role of brain-engrafted macrophages against brain injuries

BACKGROUND: Brain-resident microglia have a distinct origin compared to macrophages in other organs. Under physiological conditions, microglia are maintained by self-renewal from the local pool, independent of hematopoietic progenitors. Pharmacological depletion of microglia during whole-brain radio...

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Detalles Bibliográficos
Autores principales: Feng, Xi, Frias, Elma S., Paladini, Maria S., Chen, David, Boosalis, Zoe, Becker, McKenna, Gupta, Sonali, Liu, Sharon, Gupta, Nalin, Rosi, Susanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520231/
https://www.ncbi.nlm.nih.gov/pubmed/34654458
http://dx.doi.org/10.1186/s12974-021-02290-0