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Functional role of brain-engrafted macrophages against brain injuries
BACKGROUND: Brain-resident microglia have a distinct origin compared to macrophages in other organs. Under physiological conditions, microglia are maintained by self-renewal from the local pool, independent of hematopoietic progenitors. Pharmacological depletion of microglia during whole-brain radio...
Autores principales: | Feng, Xi, Frias, Elma S., Paladini, Maria S., Chen, David, Boosalis, Zoe, Becker, McKenna, Gupta, Sonali, Liu, Sharon, Gupta, Nalin, Rosi, Susanna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520231/ https://www.ncbi.nlm.nih.gov/pubmed/34654458 http://dx.doi.org/10.1186/s12974-021-02290-0 |
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