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Macrophage-specific RhoA knockout delays Wallerian degeneration after peripheral nerve injury in mice
BACKGROUND: Plenty of macrophages are recruited to the injured nerve to play key roles in the immunoreaction and engulf the debris of degenerated axons and myelin during Wallerian degeneration, thus creating a conducive microenvironment for nerve regeneration. Recently, drugs targeting the RhoA path...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520251/ https://www.ncbi.nlm.nih.gov/pubmed/34654444 http://dx.doi.org/10.1186/s12974-021-02292-y |