Macrophage-specific RhoA knockout delays Wallerian degeneration after peripheral nerve injury in mice

BACKGROUND: Plenty of macrophages are recruited to the injured nerve to play key roles in the immunoreaction and engulf the debris of degenerated axons and myelin during Wallerian degeneration, thus creating a conducive microenvironment for nerve regeneration. Recently, drugs targeting the RhoA path...

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Detalles Bibliográficos
Autores principales: Xu, Jiawei, Wen, Jinkun, Fu, Lanya, Liao, Liqiang, Zou, Ying, Zhang, Jiaqi, Deng, Junyao, Zhang, Haowen, Liu, Jingmin, Wang, Xianghai, Zuo, Daming, Guo, Jiasong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520251/
https://www.ncbi.nlm.nih.gov/pubmed/34654444
http://dx.doi.org/10.1186/s12974-021-02292-y

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