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Human mesenchymal stem cells derived exosomes inhibit the growth of acute myeloid leukemia cells via regulating miR-23b-5p/TRIM14 pathway

BACKGROUND: Acute myeloid leukemia (AML) is a malignancy commonly seen in adults. Previous studies indicated that TRIM14 played a tumorigenic role in various types of cancer and miR-23b-5p was down-regulated in human mesenchymal stem cell-derived exosomes (HMSC-exos) of AML patients. However, their...

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Detalles Bibliográficos
Autores principales: Cheng, Hui, Ding, Jie, Tang, Gusheng, Huang, Aijie, Gao, Lei, Yang, Jianmin, Chen, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520262/
https://www.ncbi.nlm.nih.gov/pubmed/34656078
http://dx.doi.org/10.1186/s10020-021-00393-1