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Replacement of traditional prothrombin time monitoring with the new Fiix prothrombin time increases the efficacy of warfarin without increasing bleeding. A review article

The antithrombotic effect of vitamin K antagonists (VKA) depends on controlled lowering of the activity of factors (F) II and X whereas reductions in FVII and FIX play little role. PT-INR based monitoring, however, is highly influenced by FVII, which has the shortest half-life of vitamin K-dependent...

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Detalles Bibliográficos
Autores principales: Onundarson, Pall T., Palsson, Ragnar, Witt, Daniel M., Gudmundsdottir, Brynja R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520310/
https://www.ncbi.nlm.nih.gov/pubmed/34654442
http://dx.doi.org/10.1186/s12959-021-00327-1