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Essential role of zyxin in platelet biogenesis and glycoprotein Ib-IX surface expression

Platelets are generated from the cytoplasm of megakaryocytes (MKs) via actin cytoskeleton reorganization. Zyxin is a focal adhesion protein and wildly expressed in eukaryotes to regulate actin remodeling. Zyxin is upregulated during megakaryocytic differentiation; however, the role of zyxin in throm...

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Detalles Bibliográficos
Autores principales: Yan, Rong, Ge, Xinxin, Pang, Ningbo, Ye, Honglei, Yuan, Liuxia, Cheng, Bin, Zhou, Kangxi, Yang, Mengnan, Sun, Yueyue, Zhang, Suqin, Ding, Zhongren, Luo, Jincai, Ruan, Changgeng, Dai, Kesheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520529/
https://www.ncbi.nlm.nih.gov/pubmed/34657146
http://dx.doi.org/10.1038/s41419-021-04246-x