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Essential role of zyxin in platelet biogenesis and glycoprotein Ib-IX surface expression
Platelets are generated from the cytoplasm of megakaryocytes (MKs) via actin cytoskeleton reorganization. Zyxin is a focal adhesion protein and wildly expressed in eukaryotes to regulate actin remodeling. Zyxin is upregulated during megakaryocytic differentiation; however, the role of zyxin in throm...
Autores principales: | Yan, Rong, Ge, Xinxin, Pang, Ningbo, Ye, Honglei, Yuan, Liuxia, Cheng, Bin, Zhou, Kangxi, Yang, Mengnan, Sun, Yueyue, Zhang, Suqin, Ding, Zhongren, Luo, Jincai, Ruan, Changgeng, Dai, Kesheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520529/ https://www.ncbi.nlm.nih.gov/pubmed/34657146 http://dx.doi.org/10.1038/s41419-021-04246-x |
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