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Cofilin1 oxidation links oxidative distress to mitochondrial demise and neuronal cell death

Many cell death pathways, including apoptosis, regulated necrosis, and ferroptosis, are relevant for neuronal cell death and share common mechanisms such as the formation of reactive oxygen species (ROS) and mitochondrial damage. Here, we present the role of the actin-regulating protein cofilin1 in...

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Detalles Bibliográficos
Autores principales: Hoffmann, Lena, Waclawczyk, Marcel S., Tang, Stephan, Hanschmann, Eva-Maria, Gellert, Manuela, Rust, Marco B., Culmsee, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520533/
https://www.ncbi.nlm.nih.gov/pubmed/34657120
http://dx.doi.org/10.1038/s41419-021-04242-1