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Acquired HIV drug resistance and virologic monitoring in a HIV hyper-endemic setting in KwaZulu-Natal Province, South Africa

BACKGROUND: Introduction of tenofovir (TDF) plus lamivudine (3TC) and dolutegravir (DTG) in first- and second-line HIV treatment regimens in South Africa warrants characterization of acquired HIV-1 drug resistance (ADR) mutations that could impact DTG-based antiretroviral therapy (ART). In this stud...

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Detalles Bibliográficos
Autores principales: Chimukangara, Benjamin, Lessells, Richard J., Singh, Lavanya, Grigalionyte, Indra, Yende-Zuma, Nonhlanhla, Adams, Rochelle, Dawood, Halima, Dlamini, Linda, Buthelezi, Sibonisile, Chetty, Sheldon, Diallo, Karidia, Duffus, Wayne A., Mogashoa, Mary, Hagen, Melissa B., Giandhari, Jennifer, de Oliveira, Tulio, Moodley, Pravi, Padayatchi, Nesri, Naidoo, Kogieleum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520607/
https://www.ncbi.nlm.nih.gov/pubmed/34656129
http://dx.doi.org/10.1186/s12981-021-00393-5