Tryptophan metabolism induced by TDO2 promotes prostatic cancer chemotherapy resistance in a AhR/c-Myc dependent manner

BACKGROUND: Tumor cells exhibit enhanced metabolism of nutrients to satisfy the demand of sustained proliferation in vivo. Seminal reports have presented evidence that tryptophan (Trp) metabolic reprogramming induced by aberrant indoleamine 2,3-dioxygenases could promote tumor development in several...

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Detalles Bibliográficos
Autores principales: Li, Fan, Zhao, Zhenyu, Zhang, Zongbiao, Zhang, Yan, Guan, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520630/
https://www.ncbi.nlm.nih.gov/pubmed/34657603
http://dx.doi.org/10.1186/s12885-021-08855-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520630/
https://www.ncbi.nlm.nih.gov/pubmed/34657603
http://dx.doi.org/10.1186/s12885-021-08855-9

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