Sodium phenylbutyrate inhibits Schwann cell inflammation via HDAC and NFκB to promote axonal regeneration and remyelination

BACKGROUND: Epigenetic regulation by histone deacetylases (HDACs) in Schwann cells (SCs) after injury facilitates them to undergo de- and redifferentiation processes necessary to support various stages of nerve repair. Although de-differentiation activates the synthesis and secretion of inflammatory...

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Detalles Bibliográficos
Autores principales: Yadav, Anjali, Huang, Tzu-Chieh, Chen, Szu-Han, Ramasamy, Thamil Selvee, Hsueh, Yuan-Yu, Lin, Shau-Ping, Lu, Fu-I, Liu, Ya-Hsin, Wu, Chia-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520633/
https://www.ncbi.nlm.nih.gov/pubmed/34656124
http://dx.doi.org/10.1186/s12974-021-02273-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520633/
https://www.ncbi.nlm.nih.gov/pubmed/34656124
http://dx.doi.org/10.1186/s12974-021-02273-1

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